In an enterprise IT environment, it is sometimes difficult to setup Maximo to talk with SMTP service due to networking and security restrictions. To troubleshoot SMTP configuration, in the past, we can use Telnet from CMD tool. However, in newer versions of Windows Server, Telnet is often not installed by default. In such cases, we can use PowerShell to test and confirm the SMTP and firewall setting is working before trying to configure SMTP in Maximo.
The first thing I would do is checking whether firewall has been opened so that the port used by SMTP service (e.g. port 25) is reachable from the Maximo server.